It's a tough call, since I haven't seen Babel or Letter from Iwo Jima yet. I liked Departed and loved Little Miss Sunshine, but thought CoM was a better film than those two -- it left me shaken and had me thinking back on the film for days afterward. And I don't know if I want to see Babel, frankly. I watched the director's 21 Grams back in 2003 and had very mixed feelings about it, and Babel seems to be the same sort of film.