tzikeh

I think Foreman is simply the least likely in terms of his characterization over the series. No weight-of-the-world complex (didn't marry anyone dying of brain cancer); no desperate childhood angst (father left, mother drank herself to death); no killed parents followed by being adopted by people of another culture; no oncoming guaranteed death-by-Huntington's; no disastrous monetary loss during a marriage crisis; etc.

The top three are House (impossible), Cuddy (possible, but with a new baby, highly unlikely), and Wilson (most emotional impact on House, on anti-depressants, dead girlfriend, entirely unable to maintain any romantic relationship for real, anyhow, etc....).